prediction feedforward network (Transcell Technology Inc)
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Prediction Feedforward Network, supplied by Transcell Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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1) Product Images from "TransCell: In Silico Characterization of Genomic Landscape and Cellular Responses by Deep Transfer Learning"
Article Title: TransCell: In Silico Characterization of Genomic Landscape and Cellular Responses by Deep Transfer Learning
Journal: Genomics, Proteomics & Bioinformatics
doi: 10.1093/gpbjnl/qzad008
Figure Legend Snippet: An overview of research design A . The number of RNA-seq profiles available per cell line. The numbers were collected from the ARCHS4 website ( https://maayanlab.cloud/archs4/ ). B . Prediction of measurements in six types based on gene expression data of cancer cell lines. The number of cell lines varies across data types. C . Model evaluation process. Due to the high demand for computation power, we started with a small set of measurements for each type and then scaled up to a larger set. D . Schematic of TransCell. The top 5000 features sharing similar distribution between CCLE and TCGA were first selected, followed by the creation of an autoencoder using TCGA pan-cancer tumor transcriptomes. The parameters of the TCGA encoder were then transferred to the second CCLE autoencoder for weight initializations. Afterward, a two-step pre-trained CCLE enc was extracted and linked to a prediction feedforward network. Parameters were tuned automatically (see Method for details). Note that one model is built for each molecular measurement. LASSO, least absolute shrinkage and selection operator; EN, elastic net; RF, random forest; PCA, principal component analysis; DNN, deep neural network; CCLE, Cancer Cell Line Encyclopedia; TCGA, The Cancer Genome Atlas; CCLE enc , CCLE encoder.
Techniques Used: RNA Sequencing, Gene Expression, Selection
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